Research activity

I work on the Metabolism Exploration Platform, where I conduct chemical analyses using mass spectrometry as part of human nutrition research projects.

My role includes working with researchers to understand their needs and recommend appropriate analytical methods. I oversee sample preparation, perform analyses, process data, and present results to project leaders. To ensure the reliability of results, I regularly monitor the analytical equipment to intervene in the event of deviations or malfunctions. I also supervise and train professional undergraduate students as part of their final-year internships or apprenticeships.

I am also a member of the international Workflow4Metabolomics (W4M) collective and, in particular, a trainer in metabolomics data processing using the W4M tool available on the Galaxy platform.

Most notable publications

• Metabolomic prediction of breast cancer treatment induced neurological and metabolic toxicities, Max Piffoux,Jérémie Jacquemin,Mélanie Pétéra,Stephanie Durand,Angélique Abila,Delphine Centeno,Charlotte Joly,and All, Clinical Cancer Research 2024. DOI : 10.1158/1078-0432.CCR-24-0195
• PeakForest: a multi-platform digital infrastructure for interoperable metabolite spectral data and metadata management, Nils Paulhe, Cécile Canlet, Annelaure Damont, Lindsay Peyriga, Stéphanie Durand, Catherine Deborde, Sandra Alves, Stephane Bernillon,  Thierry Berton, Raphael Bir, Alyssa Bouville, Edern Cahoreau, Delphine Centeno, Robin Costantino, Laurent Debrauwer, Alexis Delabrière, Christophe Duperier, Sylvain Emery, Amelie Flandin, Ulli Hohenester, Daniel Jacob, Charlotte Joly and All, Metabolomics, 2022.  DOI : 10.1007/s11306-022-01899-3
• ProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis, Alyssa Imbert, Magali Rompais, Mohammed Selloum, Florence Castelli, Emmanuelle Mouton-Barbosa, Marion Brandolini-Bunlon, Emeline Chu-Van, Charlotte Joly, Aurélie Hirschler, Pierrick Roger-Mele, Thomas Burger, Sophie Leblanc, Tania Sorg, Sadia Ouzia, Yves Vandenbrouck, Claudine Médigue, Christophe Junot, Myriam Ferro, Christine Carapito, Anne Gonzalez de Peredo ,François Fenaille, Christine Carapito, Yann Herault, Etienne A. Thévenot, Scientific Data, 2021. DOI : 10.1038/s41597-021-01095-3
• Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men, Blandine Comte, Stéphanie Monnerie, Marion Brandolini-Bunlon, Cécile Canlet, Florence Castelli, Emeline Chu-Van, Benoit Colsch, François Fenaille, Charlotte Joly, Fabien Jourdan, Natacha Lenuzza, Bernard Lyan, Jean-François Martin, Carole Migné, José Morais, Mélanie Pétéra, Nathalie Poupin, Florence Vinson, Etienne Thevenot, Christophe Junot, Pierrette Gaudreau, Estelle Pujos-Guillot, EBioMedicine, 2021. DOI : 10.1016/j.ebiom.2021.103440
• Assessment of protein modifications in liver of rats under chronic treatment with paracetamol (acetaminophen) using two complementary mass spectrometry-based metabolomic approaches, Carole Mast, Bernard Lyan, Charlotte Joly, Delphine Centeno, Franck Giacomoni, Jean-Francois Martin, Laurent Mosoni, Dominique Dardevet, Estelle Pujos-Guillot, Isabelle Papet, Journal of Proteomics, 2015.  DOI : 10.1016/j.jprot.2015.03.014

Other links

• https://cv.hal.science/charlotte-joly
• https://www.linkedin.com/in/charlotte-joly-b9335238/
• https://unh.clermont.hub.inrae.fr/nos-plateformes/plateforme-d-exploration-du-metabolisme-pfem