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ECREIN
University Professor - Hospital Practitioner

Research Activity

MICA : Clinical trial NCT03068663: "Characterization of microbiota (Intestinal, From Lungs, and Upper Airways) in Patients With Non-small Cell Lung Carcinoma: Observational Study." Sponsor : Centre Jean Perrin, Principal Investigator : Marc Filaire. May 2017 - This trial is the subject of a science thesis and has several objectives: A descriptive approach to the pulmonary microbiota, which is previously little known, and an analytical approach to the possible links between lung cancer, immunity, and microbiota. Co-supervision of this thesis with Professor Édith Filaire.

REXOCHIR Clinical trial NCT03020251 REXOCHIR “Effects of Preoperative Rehabilitation in Patients Resected for Lung Cancer”. Promoter CJP, Principal Investigator : Marc Filaire. This study is the subject of a science thesis and is part of a larger project to redesign the management of care and patients in surgery: Improved rehab in surgery. Co-supervision of this thesis with Professor Frédéric Costes.

Participation in clinical research studies in thoracic surgery and retrospective case studies.

Most notable publications

  • Tardy MM, Filaire M, Patoir A, Gautier-Pignonblanc P, Galvaing G, Kwiatkowski F, Costes F, Richard R. Exercice cardiac output limitation in pectus excavatum. J Am Coll Cardiol 2015 ;66(8):976-977.
  • Bingula R, Filaire M, Radosevic-Robin N, Bey M, Berthon JY, Bernalier-Donadille A, Vasson MP, Filaire E. Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer. J Oncol. 2017;2017:5035371. Review.
  • Laurent H, Galvaing G, Thivat E, Coudeyre E, Aubreton S, Richard R, Kwiatkowski F, Costes F, Filaire M. Effect of an intensive 3-week preoperative home rehabilitation programme in patients with chronic obstructive pulmonary disease eligible for lung cancer surgery: a multicentre randomised controlled trial. BMJ Open. 2017 Nov 12;7(11):e017307.
  • Bingula R, Filaire M, Radosevic-Robin N, Berthon JY, Bernalier-Donadille A, Vasson MP, Thivat E, Kwiatkowski F, Filaire E. Characterisation of gut, lung, and upper airways microbiota in patients with non-small cell lung carcinoma: Study protocol for case-control observational trial. Medicine (Baltimore). 2018 Dec;97(50):e13676.
  • Laurent H, Aubreton S, Galvaing G, Pereira B, Merle P, Richard R, Costes F, Filaire M.Preoperative respiratory muscle endurance training improves ventilatory capacity and prevents pulmonary postoperative complications after lung surgery: a randomized controlled trial. Eur J Phys Rehabil Med. 2019 Sep 4.

Other link

ECREIN