Due to the major role of muscle within the body, the objective is to maintain health and well-being by combining physical activity and the fight against a sedentary lifestyle, to maintain muscle mass and qualities, and therefore mobility, and limit co-morbidities.

Research activities

Two main objectives are defined:

1) Increase or even maintain muscle mass and quality, as well as physical fitness in various physiological (aging) or pathological situations accompanied by metabolic disorders (type 2 diabetes, obesity, cancer), in relation to the level of total physical activity, the type and intensity of physical activity, and the total time spent in sedentary activities. The objective is to prioritize reducing the time spent in sedentary activities and replacing it with either low-intensity PA or even moderate-intensity PA later on.

2) Develop innovative strategies using new information and communication technologies to implement and maintain long-term physical activity in subjects with chronic pathologies that affect mobility. The secondary objectives are to evaluate variations in physical activity and sedentary lifestyle over time and the impact of a reduction in sedentary time on quality of life, physical performance, and cardiometabolic comorbidities. The hypothesis is that the use of a smartphone with objective measurement of low-intensity physical activity and sedentary lifestyle should enable lasting changes in behavior and thus promote the follow-up of recommendations more adapted to this sedentary and inactive population. As has been demonstrated in healthy subjects, we can expect significant effects on health and comorbidities, with greater patient involvement.

Most notable publications

• Thivel D, Doucet E, Julian V, Cardenoux C, Boirie Y, Duclos M. Nutritional compensation to exercise- vs. diet-induced acute energy deficit in adolescents with obesity. Physiol Behav. 2017;176:159-64M.
• Duclos M, G. Fleury, P. Lacomme, R. Phan, L. Ren, S. Rousset. An Acceleration Vector Variance based Method for Energy Expenditure Estimation in Real-Life Environment with a Smartphone/Smartwatch Integration. Expert Systems With Applications, 2016, doi 10.1016/j.eswa.2016.07.021.
• Duclos M, Tabarin A. Exercise and the Hypothalamo-Pituitary-Adrenal axis. Front Horm Res 2016, 47, 12-26.
• Lanhers C., Duclos M., Guttmann A., Coudeyre E., Pereira B., & Ouchchane L.  General Practitioners' Barriers to Prescribe Physical Activity: The Dark Side of the Cluster Effects on the Physical Activity of Their Type 2 Diabetes Patients. PLoSONE. Oct 15; 10 (10): e0140429, 2015.
• Duclos M, Ouerdani A, Mormède P, Konsman JP. Food-restriction-induced hyperactivity: addiction or fleeing famine? Psychoneuroendocrinology 38(6) 884-97, 2013.
• Duclos M, Coudeyre E, Ouchchane L. General practioners' barriers to physical activity negatively influence type 2 diabetes mellitus patients' involvement in regular physical activity. Diabetes Care 34 (7): e122, 2011

Career and CV Elements

University Professor - Hospital Practitioner (Physiology), Head of the Sports Medicine and Functional Explorations Department, CHU G. Montpied, Clermont-Ferrand

University degrees :
DEA (Master of Advanced Studies) in Biology and Health (1993)
Doctorate in Medicine (1994) specializing in Endocrinology, Metabolism, and Nutritional Diseases (DES)
Doctorate from the University of Bordeaux 2 (1997)
Habilitation to Supervise Research (2001)

Participation in national expert assessments or ministerial commissions :
- INSERM expert assessment on "the beneficial effects of physical activity" (2006-2008)
- Ministerial Commission on Physical Activity, Prevention, and Health (2008)
- ANSES expert assessment : "Assessment of risks associated with weight-loss dietary practices" (2010)
- French National Sports and Olympic Committee (CNOSF): member of the Women's Sports Commission, member of the CNOSF Medical Commission, co-chair of the Sports Activity-Health Commission (Dr. A. Calmat)
- French Agency for Food, Environmental, and Occupational Health and Safety (ANSES): expert working group on "PNNS - revision of benchmarks relating to physical activity" (2013-2015)
- French National Cancer Institute: expert working group on "Physical Activity during and after cancer" (2013-2016)
- Fondation de France: Expert for the "Sport, Health, and Integration" Committee (May 6, 2015-…)
- Haute Autorité de Santé: Member of the working group for the prescription of physical activity and sport for health (2017-…)
- Ministry of Sports: Scientific Advisor for sport and health since September 2013
- National Observatory of Physical Activity and Sedentary Lifestyle: Founder and Chair of the Scientific Council
- International Chair on Cardiometabolic Risk: Expert (Professor JP Despres, Université Laval, Quebec) (March 2013-…)
- European Union-WHO: French expert (focal point responsible for implementing the recommendation on the cross-disciplinary promotion of PA)

Other links

ASMS

https://www.linkedin.com/in/martine-duclos-a240ab51/