My work is in the field of metabolomics, a key discipline for exploring and better understanding metabolic mechanisms in living organisms. On the one hand, I identify potential biomarkers of metabolic deregulation, associated with the development of pathologies and/or food consumption in the context of nutritional and/or epidemiological studies by mass spectrometry. On the other hand, I develop innovative methods for profiling and annotation of the metabolome in order to improve the identification of metabolites.

Most notable publications

• Max Piffoux (1) , Jérémie Jacquemin (2) , Mélanie Pétéra (3) , Stephanie Durand (3) , Angélique Abila (3) , Delphine Centeno (3) , Charlotte Joly (3) , Bernard Lyan (3) , Anne-Laure Martin (4) , Sibille Everhard (4) , Sandrine Boyault (2) , Barbara Pistilli (5) , Marion Fournier (6) , Philippe Rouanet (7) , Julie Havas (5) , Baptiste Sauterey (8) , Mario Campone (8) , Carole Tarpin (9) , Marie-Ange Mouret-Reynier (10) , Olivier Rigal (11) , Thierry Petit (12) , Christine Lasset (2) , Aurélie Bertaut (13) , Paul Cottu (14) , Fabrice Andre (5) , Ines Vaz-Luis (5) , Estelle Pujos-Guillot (3) , Youenn Drouet (2) , Olivier Trédan (2). Metabolomic Prediction of Breast Cancer Treatment Induced Neurological and Metabolic Toxicities. Clinical Cancer Research 2024. 30 (20), 4654–4666. https://doi.org/10.1158/1078-0432.CCR-24-0195
• Pla, R.; Brandolini-Bunlon, M.; Pujos-Guillot, E.; Durand, S.; Centeno, D.; Pyne, D.; Toussaint, J.-F.; Hellard, P. Non-Targeted Metabolomics Analyses by Mass Spectrometry to Explore Metabolic Stress after Six Training Weeks in High Level Swimmers. Journal of Sports Sciences 2021, 39 (9), 969–978. https://doi.org/10.1080/02640414.2020.1851933.
• Galan, P.; Hercberg, S.; Rossary, A.; Demidem, A.; Vasson, M.-P.; Partula, V.; Deschasaux, M.; Srour, B.; Latino-Martel, P.; Druesne-Pecollo, N.; Kesse-Guyot, E.; Durand, S.; Pujos-Guillot, E.; Manach, C.; Touvier, M. Untargeted Plasma Metabolomic Profiles Associated with Overall Diet in Women from the SU.VI.MAX Cohort. European Journal of Nutrition 2020, 59 (8), 3425–3439. https://doi.org/10.1002/jms.3957.
• Theron, L.; Centeno, D.; Coudy-Gandilhon, C. C.; Pujos-Guillot, E.; Astruc, T.; Remond, D.; Barthélémy, J.-C.; Roche, F.; Feasson, L.; Hébraud, M.; Béchet, D.; Chambon, C. A Proof of Concept to Bridge the Gap between Mass Spectrometry Imaging, Protein Identification and Relative Quantitation: MSI LC-MS/MS-LF. Proteomes 2016, 4 (4), 32. https://doi.org/10.3390/proteomes4040032. 

Other links

Metabolism exploration platform (PFEM)

https://cv.hal.science/delphine-centeno