Marie-Anne VERNY

Activity

My mission is focused on developing techniques to assess the state of the cardiovascular system, and in particular vascular function, in humans and animal models. The goal is to be able to identify cardiovascular risk early and, to this end, to develop robust markers that can be applied at a population level.

• Measurement of soluble markers of endothelial injury (von Willebrand factor) and endothelial activation (adhesion molecules: sICAM-1 and sVCAM-1), circulating NO pool, endothelial microparticles (EMPs), and specific microRNAs (miRNAs).
• I am involved in all of the Nutrivasc team's clinical studies.
• Responsible for the technical platform dedicated to the physiological exploration of vascular function using non-invasive methods in humans. Several methods for exploring vascular function are implemented in clinical studies :

                        - Endothelium-dependent vasodilation
                        - Arterial stiffness

• Immuno- histochimie, microscopie

Publications

• Barber-Chamoux, N., Milenkovic, D., Verny, M. A., Habauzit, V., Pereira, B., Lambert, C., Richard, D., Boby, C., Mazur, A., Lusson, J. R., Dubray, C. and Morand, C. (2018). "Substantial Variability Across Individuals in the Vascular and Nutrigenomic Response to an Acute Intake of Curcumin: A Randomized Controlled Trial." Mol Nutr Food Res 62(5).
• Habauzit, V., Verny, MA., Milenkovic, D., Barber-Chamoux, N., Mazur, A., Dubray, C.,Morand, C. Flavanones protect from arterial stiffness in postmenopausal women consuming grapefruit juice for 6-months: A randomized controlled crossover trial. American Journal of Clinical Nutrition . 2015
• Gladine, C.,Zmojdzian, M., Joumard-Cubizolles, L., Verny, M. A., Comte, B., Mazur, A.The omega-3 fatty acid docosahexaenoic acid favorably modulates the inflammatory pathways and macrophage polarization within aorta of LDLR-/- mice. Genes and Nutrition; vol 9 (5). 2015.